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Posted by
Two Blokes Jun 30 -
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In the Phase 2 MINDFuL trial of XPro\u2122 in patients with early Alzheimer's Disease (AD) with biomarkers of inflammation, the modified intent-to-treat (mITT) population (n=200) did not meet the primary cognitive endpoint (EMACC), however in a predefined population of amyloid-positive early AD patients with two or more biomarkers of inflammation (n=100), a benefit of XPro\u2122 treatment over placebo was observed in cognitive, behavioral and biological endpoints.